Addressing regional problems in the field of environmental protection is carried out within the framework of targeted environmental programs, documents reflecting the essence of the ongoing regional environmental policy. Approved indicators monitor the effectiveness of its implementation. In many regions, the results of the implementation of previous programs are disappointing, which is due to many reasons. The following questions remain unanswered: how the national and territorial interests are combined in the development of programs, how the content of the program tasks and the indicators of their effectiveness correspond to the targets of these documents? The hypothesis of the study is that the imperfection of regional environmental programs complicates their effectiveness. The purpose of the study is to analyze the content of the used indicators that are fixed in the environmental programs of the most economically developed regions of the Far Eastfor identification of the highest priority regional environmental tasks and the focus of their solution to improve the system of indicators in subsequent revisions of environmental protection documents. The information base includes regulatory documents in the field of environmental security in Russia, statistics data, rules and regulations on the development, implementation and evaluation of effectiveness state and municipal programs, national and regional programs on "Environmental protection" of the Far East subjects, adopted for the period 2020-2025. Having analysed 211 indicators proposed in the regional programs in order to determine the share of the most significant for environmental protection, the correlation of their content with the specifics of regional development has been established. It has been determined that more than 50% of all indicators relate to direct improvement of the environment.  During the analysis, the main shortcomings in the selection of the indicators have been identified: 16% of indicators are not correct in content; 41% of indicators do not have clear quantitative benchmarks, which does not always make it possible to assess the achievement of objectives. The solution of the indicated issues will allow expanding the theoretical knowledge in terms of the formation of regional environmental policy and enriching the practice of regional interpretation and solution of accumulated problems, which is demanded due to the limited number of works in this area.